Abstract:Slope stability is very important for open-pit mine engineering. In order to further study the sensitivity of the influencing factors of slope stability in a mine in Yunnan, this paper accurately determines the four factors that have the greatest impact on the slope stability of the mine according to the field exploration and rock mechanics laboratory tests. Then, the test group is designed by an orthogonal test, and then the slope safety factor is calculated based on the strength reduction method. Finally, the range analysis method and variance analysis method are used to compare and verify the experimental results, which fully guarantees the comprehensiveness and accuracy of the analysis. The final results show that the four factors have a significant impact on the slope of the mine. The sensitivity of the influencing factors of the slope stability of the mine from large to small is cohesion > horizontal seismic acceleration > internal friction angle > final slope angle; the order of sensitivity obtained by range analysis and variance analysis is consistent, which can be checked mutually. This study can provide some reference for the design and reinforcement of similar open-pit mine slopes.